shock
Conditions
Interventions
Gold Standard:investigators with expertise in image processing of sublingual microcirculation
Index test:deep learning algorithms
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Meet the definition of shock: despite adequate fluid resuscitation, vasopressors are required to maintain MAP = 65 mmHg, and serum lactate > 2 mmol/L, which are indicators of hypotension and hypoperfusion; 3.Informed consent (by the patient or legal representative) can be obtained within 24 hours after the patient is diagnosed with shock and admitted to the ICU;
Exclusion criteria
Exclusion criteria: 1.Severe trauma, deformity, surgical history, or active bleeding in the sublingual region that affects microcirculation image acquisition; 2.Patients who cannot tolerate weaning from non-invasive ventilation; 3.Pregnant or breastfeeding women; 4.Patients unable to cooperate or unable to provide valid informed consent due to language barriers, severe dementia, or mental illness; 5.Any other condition deemed by the investigator to be unsuitable for participation in this study (e.g., high risk of severe coagulation dysfunction); 6.Concurrent participation in other therapeutic studies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sublingual microcirculation parameters;The consistency between AI algorithms and the consensus scores provided by human experts; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in SOFA score;Change in APACHE II score;Length of stay in the ICU;28-day all-cause mortality;Lactate clearance rate; | — |
Countries
China
Contacts
Public ContactHongping Qu
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed