Postoperative Nausea and Vomiting
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age >= 18 years. ASA physical status classification I-III. Scheduled for elective surgery under general anesthesia with a planned postoperative analgesic regimen using intravenous patient-controlled analgesia. Voluntarily participate in the study and provide written informed consent.
Exclusion criteria
Exclusion criteria: Emergency surgery. Presence of gastrointestinal obstruction, active symptoms of nausea and vomiting, or severe gastroesophageal reflux disease. Severe hepatic or renal dysfunction (Child-Pugh class C or eGFR 3 months) or regular use of antiemetic medications. Known or suspected difficult airway. Cognitive impairment, psychiatric disorders, or language barriers that would prevent cooperation with study follow-up. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of PONV within 24 hours postoperatively.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to the first onset of PONV.;The severity of PONV.;The types, dosages, and frequency of rescue antiemetic drugs used due to PONV within the first 24 hours after surgery.;The types, dosages, and frequency of rescue antiemetic drugs used due to PONV from 24 to 48 hours after surgery.; | — |
Countries
China
Contacts
The Affiliated Hospital of Xuzhou Medical University