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The Impact of Preoperative Fasting Duration on Postoperative Nausea and Vomiting in Patients Using Patient-Controlled Analgesia: A Prospective Cohort Study

The Impact of Preoperative Fasting Duration on Postoperative Nausea and Vomiting in Patients Using Patient-Controlled Analgesia: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119071
Enrollment
Unknown
Registered
2026-02-14
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Interventions

Patients were grouped based on the duration of preoperative fasting.:None

Sponsors

Department of Anesthesiology,The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years. ASA physical status classification I-III. Scheduled for elective surgery under general anesthesia with a planned postoperative analgesic regimen using intravenous patient-controlled analgesia. Voluntarily participate in the study and provide written informed consent.

Exclusion criteria

Exclusion criteria: Emergency surgery. Presence of gastrointestinal obstruction, active symptoms of nausea and vomiting, or severe gastroesophageal reflux disease. Severe hepatic or renal dysfunction (Child-Pugh class C or eGFR 3 months) or regular use of antiemetic medications. Known or suspected difficult airway. Cognitive impairment, psychiatric disorders, or language barriers that would prevent cooperation with study follow-up. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
The incidence of PONV within 24 hours postoperatively.;

Secondary

MeasureTime frame
The time to the first onset of PONV.;The severity of PONV.;The types, dosages, and frequency of rescue antiemetic drugs used due to PONV within the first 24 hours after surgery.;The types, dosages, and frequency of rescue antiemetic drugs used due to PONV from 24 to 48 hours after surgery.;

Countries

China

Contacts

Public ContactSun Qianwei; Wu Jiao

The Affiliated Hospital of Xuzhou Medical University

15950670080@163.com+86 159 5067 0080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026