Sepsis-associated encephalopathy
Conditions
Interventions
Non-sepsis-associated encephalopathy group:none
Sepsis-associated encephalopathy group:none
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 91 Years
Inclusion criteria
Inclusion criteria: 1. Patients who have undergone elective or emergency surgery 2. Age >=18 years old; 3. Comply with the international diagnostic criteria for sepsis SEPSIS 3.0 jointly released by SCCM and ESICM in 2016 ; 4. The diagnostic criteria of SAE are based on the Glasgow Coma Scale (GCS). If the GCS is less than 15 points or there are progressive and clearly recorded neuropsychiatric or cognitive impairments in patients with sepsis, including inattention, delirium, disorientation, consciousness disorders and epileptic seizures; 5. The clinical data are complete.
Exclusion criteria
Exclusion criteria: 1. Primary central nervous system diseases (such as intracranial infections, brain trauma, cerebrovascular diseases, immune encephalitis, etc.); 2. Changes in consciousness state caused by metabolic diseases, such as hypoglycemia, hyperglycemia, hepatic encephalopathy, pulmonary encephalopathy, uremic encephalopathy, etc. 3. Genetic diseases that affect neuropsychological behavior; 4. Malignant tumor; 5. Long-term alcohol abuse or drug use; 6. Poisoning by drugs or poisons; 7. Recently received cardiac resuscitation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sequential Organ Failure Assessment;Acute Physiology and Chronic Health Evaluation;The duration of intraoperative hypotension;The area of intraoperative hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Countries
China
Contacts
Public ContactQiying Shen
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed