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The correlation between the sugar sheath and the absence of cerebral reperfusion as well as hemorrhagic transformation

A Study on the Correlation between Plasma Polysaccharide-Coated Degradation Products after Successful Vascular Reperfusion in Acute Ischemic Stroke Patients and Cerebral Ischemia Reperfusion and Symptomatic Intracranial Hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119039
Enrollment
Unknown
Registered
2026-02-14
Start date
2025-02-14
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Observation group:None

Sponsors

Guabgzhou First People‘s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who underwent mechanical thrombectomy for acute anterior circulation stroke at our stroke center; 2.The pre-treatment mRS score was 0-2, and the pre-treatment NIHSS score was >=4. 3.Successful recanalization after mechanical thrombectomy, that is, mTICI>= 2b; 4.Imaging evaluations were conducted before the operation and within 24 hours to 1 week after the operation, and the imaging quality was good.

Exclusion criteria

Exclusion criteria: 1.Excluding patients who are unable to undergo endovascular treatment or who have only received endovascular thrombolysis; 2.Exclude stroke types such as hemorrhagic stroke, transient ischemic attack, lacunar infarction, posterior circulation infarction, and pseudo-stroke. 3.Exclude cerebral venous thrombosis; 4.Exclude cases where re-occlusion or new intracranial occlusion is observed on follow-up imaging. 5.Excluding cases where perfusion imaging assessment cannot be obtained or where the quality of imaging is poor;

Design outcomes

Primary

MeasureTime frame
24-hour NIHSS score ;90-day mRS score;no reperfusion;

Countries

China

Contacts

Public ContactLi Xing

Guabgzhou First People‘s Hospital

eylixing@scut.edu.cn+86 20 8104 8888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026