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Clinical Validation of a Deep Learning–Based PET/CT Image Processing Approach for Lymphoma

Development and Clinical Validation of a Deep Learning Model Based on Lymphoma PET/CT Imaging and Deauville Scoring

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119037
Enrollment
Unknown
Registered
2026-02-14
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lymphoma

Interventions

Gold Standard:The reference standard in this study was independently determined by two senior physicians who were dual-certified in radiology and nuclear medicine and had extensive experience in inter
Index test:The index test in this study is a deep learning–based denoising low-dose CT image processing method, in which simulated quarter-dose CT images are denoised using a deep learning model and s

Sponsors

The Central Hospital of Xiangtan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with lymphoma who underwent whole-body [18F]FDG PET/CT examinations; 2. Imaging data that can be fully retrieved from the PACS system; 3. Availability of both baseline PET/CT and at least one follow-up PET/CT examination (applicable only to patients included in the clinical evaluation).

Exclusion criteria

Exclusion criteria: 1. Missing or incomplete PET or CT imaging data; 2. Images with severe artifacts or clearly insufficient quality that impair lesion detection, disease staging, or treatment response assessment; 3. Insufficient clinical or imaging information to establish reference standards for diagnosis, staging, or treatment response evaluation.

Design outcomes

Primary

MeasureTime frame
Root Mean Square Error, Structural Similarity Index, and Peak Signal-to-Noise Ratio;Sensitivity for hypermetabolic lesions;Specificity for hypermetabolic lesions;ROC-AUC for hypermetabolic lesions;

Countries

China

Contacts

Public ContactMantian Liao

The Central Hospital of Xiangtan

410431906@qq.con+86 732 5828 6412

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026