Chemotherapy-related diarrhea in colorectal cancer
Conditions
Interventions
Control group:Conventional basic internal medicine nursing treatment + Auricular acupressure (seedless)
Experimental group:Internal medicine routine care + Auricular point pressing (with seeds)
Sponsors
The First Affiliated Hospital of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 80 years old, gender and ethnicity are not restricted; 2. Meet the Western medical diagnosis criteria for colorectal cancer; 3.Patients with colorectal cancer who are currently undergoing chemotherapy regimens containing irinotecan or 5-Fu; 4.Meet the diagnostic criteria for diarrhea and syndromes in both traditional Chinese and Western medicine after using chemotherapy drugs,before chemotherapy, defecation was normal, and there was no habitual diarrhea; 5.Diarrhea grade is 1-3; 6.Karnofsky Performance Status Score (KPS) >= 60 points; 7. Ear is intact without injury, no scars, not allergic to alcohol and tape, and suitable for auricular acupressure; 8. Conscious, voluntarily participating in this study, and signing the informed consent form. Note: Only patients meeting all 8 criteria can be included in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with diarrhea caused by other diseases;patients who have been taking drugs that affect intestinal function for a long time; 2. Patients with severe primary diseases such as cardiovascular diseases (unstable angina pectoris, severe arrhythmia, myocardial infarction within 6 months), liver diseases (acute renal failure, grade C liver cirrhosis), kidney diseases (chronic renal failure), digestive tract diseases (active gastrointestinal bleeding, acute phase of inflammatory bowel disease, intestinal obstruction), or other tumors; 3.Lactating women or those planning to get pregnant within the next three months; 4. Patients currently participating in or recently participating in other studies; 5. Patients with inflammation, eczema, ulcers, frostbite or large scar tissue on the ear skin; 6.Patients with severe infections. Note: All patients meeting any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Daily frequency of defecation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score;Traditional Chinese Medicine Symptom Score;Adverse Event Assessment Questionnaire;Grading of stool characteristics; | — |
Countries
China
Contacts
Public ContactChen Lingxuan
The First Affiliated Hospital of Xiamen University
Outcome results
None listed