Gastrointestinal disease
Conditions
Interventions
Experimental group:Provide real transcutaneous auricular vagus nerve stimulation
Control group:Provide fake transcutaneous auricular vagus nerve stimulation
Sponsors
Affiliated Hospital of Southwest Medicial University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients with physical condition I-II as defined by the American Society of Anesthesiologists (ASA); 2. Aged between 18 and 85 years old; 3. Diagnosed with mucosal and submucosal lesions of the esophagus, stomach (such as early cancer, high-grade intraepithelial neoplasia, large flat polyps, etc.) or the colon and rectum, and scheduled to receive elective ESD treatment.
Exclusion criteria
Exclusion criteria: 1. History of chronic pain or long-term use of analgesics before the surgery; 2. Previous history of ESD surgery; 3. Mental illness; 4. Skin diseases affecting the auricle area; 5. Neuro-muscular diseases; 6. Complicated with serious diseases such as heart, lung, kidney, brain, and blood; 7. Have a tendency to severe bleeding; 8. Participated in other concurrent clinical trials; 9. Refused to cooperate with the study or refused to sign the informed consent form due to communication difficulties or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting pain score at 24 hours postoperatively;Postoperative opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting;Incidence of postoperative urinary retention;Time to first flatus/defecation;Postoperative anxiety score;Postoperative sleep quality; | — |
Countries
China
Contacts
Public ContactXiaowei Tang
Affiliated Hospital of Southwest Medicial University
Outcome results
None listed