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The Impact of Early Feeding on Postoperative Complications and Recovery Following Colorectal Endoscopic Submucosal Dissection

The Impact of Early Feeding versus Delayed on Postoperative Complications and Recovery Following Colorectal Endoscopic Submucosal Dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119022
Enrollment
Unknown
Registered
2026-02-14
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyps

Interventions

Early feeding group:Two hours after ESD, drink 50 ml of water. If there is no discomfort such as nausea, vomiting, black stool, bloody stool, or severe abdominal pain, start taking enteral nutrition s
Regular open diet:Regular open diet

Sponsors

Zhongda Hospital Affiliated to Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old, with no gender restrictions; 2. Preoperatively diagnosed with colorectal adenoma or early colorectal cancer without lymph node or vascular metastasis, and meeting the indications for ESD treatment; all lesions were evaluated preoperatively by magnifying endoscopy (ME), endoscopic ultrasound (EUS), and chest and abdominal imaging. 3.American Society of Anesthesiologists (ASA) classification of I-III grade, and able to tolerate ESD operation; 4. Patients provided informed consent, voluntarily participated in this study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients who do not meet the inclusion criteria; 2.Those with contraindications to ESD; 3. Patients with multiple sites in the colorectum requiring ESD treatment; 4. Those experiencing major gastrointestinal bleeding or perforation during ESD; 5. Patients who cannot tolerate or cooperate with ESD procedures; 6. Those with severe coagulation disorders or on anticoagulant drugs that cannot be safely discontinued during the perioperative period; 7. Patients with severe cardiopulmonary insufficiency, liver or kidney dysfunction, etc.; 8. Those with severe cognitive impairment or mental disorders, unable to cooperate with postoperative dietary plans and evaluations; 9. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Delayed hemorrhage;

Secondary

MeasureTime frame
Delayed perforation;Postoperative abdominal pain;Postoperative abdominal distension;The time of first anal exhaust/defecation;Total postoperative hospital stay;Total medical expenses;

Countries

China

Contacts

Public ContactRuihua Shi, Lu Qin

Zhongda Hospital Affiliated to Southeast University

luqin81287@163.com+86 136 4516 0697

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026