Endovascular Therapy for Medium Vessel Occlusion in Ischemic Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old and = 6 points; Proximal moderate vascular occlusion: Clearly occluded at the M2 segment of the middle cerebral artery, the P1 segment of the posterior cerebral artery, or the A1 segment of the anterior cerebral artery; 3. The time from onset to admission meets any of the following conditions: Within the window (onset 4.5 hours and <= 24 hours), not eligible for intravenous thrombolysis (such as exceeding the time window, presence of thrombolysis contraindications, etc.); 4. The patient or their legal representative has signed the informed consent form; 5. It is expected that a 90-day follow-up can be completed.
Exclusion criteria
Exclusion criteria: 1. History of severe intracranial hemorrhage or other severe bleeding tendencies (such as coagulation dysfunction, active bleeding, etc.); 2. Severe liver and kidney dysfunction, advanced malignant tumors, expected survival period = 3 points (indicating existing basic functional impairment); 5. Unable to cooperate with relevant examinations and follow-up; 6. The investigator determines that there are other situations that are not suitable for inclusion in the study (such as mental illness, refusal of treatment, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the RANKIN scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Revascularization rate;Incidence of adverse events;The differences in benefits among different subgroups;Change in NIHSS score between admission and discharge;Hospitalization period;Medical expenses during hospitalization; | — |
Countries
China
Contacts
Nanjing Pukou People's Hospital (Southeast University Affiliated Liangjiang Hospital)