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Endovascular Therapy for Medium Vessel Occlusion: A Prospective Multicenter Study in Patients With Severe Deficits and Proximal Occlusions

Endovascular Therapy for Medium Vessel Occlusion: A Prospective Multicenter Study in Patients With Severe Deficits and Proximal Occlusions

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600119020
Enrollment
Unknown
Registered
2026-02-14
Start date
2026-02-14
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endovascular Therapy for Medium Vessel Occlusion in Ischemic Stroke

Interventions

EVT/Conservative Treatment Observation Group:None

Sponsors

Nanjing Pukou People's Hospital (Southeast University Affiliated Liangjiang Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old and = 6 points; Proximal moderate vascular occlusion: Clearly occluded at the M2 segment of the middle cerebral artery, the P1 segment of the posterior cerebral artery, or the A1 segment of the anterior cerebral artery; 3. The time from onset to admission meets any of the following conditions: Within the window (onset 4.5 hours and <= 24 hours), not eligible for intravenous thrombolysis (such as exceeding the time window, presence of thrombolysis contraindications, etc.); 4. The patient or their legal representative has signed the informed consent form; 5. It is expected that a 90-day follow-up can be completed.

Exclusion criteria

Exclusion criteria: 1. History of severe intracranial hemorrhage or other severe bleeding tendencies (such as coagulation dysfunction, active bleeding, etc.); 2. Severe liver and kidney dysfunction, advanced malignant tumors, expected survival period = 3 points (indicating existing basic functional impairment); 5. Unable to cooperate with relevant examinations and follow-up; 6. The investigator determines that there are other situations that are not suitable for inclusion in the study (such as mental illness, refusal of treatment, etc.).

Design outcomes

Primary

MeasureTime frame
Improvement of the RANKIN scale score;

Secondary

MeasureTime frame
Revascularization rate;Incidence of adverse events;The differences in benefits among different subgroups;Change in NIHSS score between admission and discharge;Hospitalization period;Medical expenses during hospitalization;

Countries

China

Contacts

Public ContactHu Di

Nanjing Pukou People's Hospital (Southeast University Affiliated Liangjiang Hospital)

382907028@qq.com+86 180 6185 0523

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026