Gastroscopy and colonoscopy
Conditions
Interventions
A Group (Corrected Body Weight):Cycloprofen, induction dose 0.4 mg/kg (calculated by corrected body weight), maintenance dose 1 mg/kg×h (calculated by corrected body weight)
B Group (Total Body Weight):Cycloprofen, induction dose 0.4 mg/kg (calculated by total body weight), maintenance dose 1 mg/kg×h (calculated by total body weight)
C Group (Ideal Body Weight):Cycloprofen, induction dose 0.4 mg/kg (calculated by ideal body weight), maintenance dose 1 mg/kg×h (calculated by ideal body weight)
Sponsors
The Seventh Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. It to the indications of painless colonoscopy and can be tolerated; 2. The American Association of Anesthesiologists (ASA) classification as Grade I-II; 3. Age: 18-64 years old; 4. Body mass index (BMI) >= 25 kg/m^2; 5. The patient voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergic to the drugs used in this research; 2. Coronary arteriosclerosis or grade II or above cardiac function; 3. A history of upper respiratory tract infection within 2 weeks; 4. Asthma attack period, uncontrolled hypertension and diabetes, hyperthyroidism or hypothyroidism; 5. Have mental system disorders and cognitive dysfunction; 6. There is a history of abuse of psychotropic drugs and anesthetics. 7. Abnormal liver and kidney functions; 8. Pregnant or lactating women; 9. Age 64 years old; 10. The subjects voluntarily withdrew from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression (SPO2 < 95%); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in patient vital signs;Total dose of cycloprofen;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactChi Xinjin
The Seventh Affiliated Hospital, Sun Yat-sen University
Outcome results
None listed