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Effect of Liposomal Bupivacaine on Rebound Pain Following Brachial Plexus Block

Effect of Liposomal Bupivacaine on Rebound Pain Following Brachial Plexus Block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600119006
Enrollment
Unknown
Registered
2026-02-13
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rebound Pain Following Brachial Plexus Block

Interventions

LB:Brachial plexus block was performed using 10 mL (133 mg) of liposomal bupivacaine mixed with 10 mL of normal saline.
R:Brachial plexus block was performed using 0.375% ropivacaine 20ml.

Sponsors

Ganzhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Under Brachial Plexus Block for Arthroscopic Shoulder Surgery, age 18–60 years, ASA physical status I–III.

Exclusion criteria

Exclusion criteria: 1. Cognitive or psychiatric dysfunction that is expected to impair compliance with the study protocol; 2. Known allergy to local anesthetics or contraindications to conventional postoperative analgesics; 3. Infection at the nerve block injection site; 4. Preoperative daily opioid use for >2 weeks; 5. Patients with peripheral neuropathy or injury, as well as those with severe renal, hepatic, or cardiovascular diseases.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative rebound pain;

Secondary

MeasureTime frame
Duration of rebound pain;Numeric rating scale;Time to first request for analgesia; total analgesic consumption via PCA pump over 48h postoperativel;incidence of rescue analgesia within 48 hours postoperatively;incidence of adverse events within 48 hours postoperatively;

Countries

China

Contacts

Public ContactYisheng Huang

Ganzhou People's Hospital

hys1619@i.smu.edu.cn+86 157 7973 6210

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026