Postoperative delirium
Conditions
Interventions
Experimental Group:Once before and once after surgery, stimulate for 20 minutes using a tACS device, with electrodes placed on the prefrontal cortex.
Control Group:Sham stimulation
Sponsors
The Second Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Age>=65 years and <90 years, any gender; (2) Scheduled to undergo non-cardiac surgery under general anesthesia, ASA class I–III; (3) Willing to participate and signed the informed consent form, complete clinical data, and able to complete follow-up visits.
Exclusion criteria
Exclusion criteria: (1) Refusal to participate in this study; (2) Dementia; inability to communicate before surgery due to coma, visual or auditory impairment, or speech disorders; (3) Pre-existing schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis before surgery; (4) Severe dysfunction of the heart, brain, kidney, or liver, or cranial injuries; patients undergoing emergency surgery or intracranial surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium within 3 days after surgery;Incidence of postoperative adverse events within 3 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative EEG features;Preoperative Frail Scale Score;Preoperative MMSE Scale Score;Preoperative PSQI Scale Score;AIS score within 3 days after surgery;HADS scores before surgery and 3 days after surgery;NRS assessment of resting and activity pain;QoR-15 Score within 3 days after surgery; | — |
Countries
China
Contacts
Public ContactMuhuo Ji
The Second Affiliated Hospital of Nanjing Medical University
Outcome results
None listed