Severe Brain Injury
Conditions
Interventions
Observation group:None
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: This study included patients aged 18 years and older who met the following criteria: 1. Diagnosed with ABI (including subarachnoid hemorrhage, intracerebral hemorrhage, etc.) at ICU admission or during ICU treatment; 2. Met the criteria for calculating the CALLY index (albumin level, lymphocyte count, C-reactive protein level) at ICU admission or during ICU treatment; 3. Had a GCS score <=12 at ICU admission or at the initial time of ICU treatment.
Exclusion criteria
Exclusion criteria: 1.Patients with an ICU stay of less than 72 hours or those who died on the day of ICU admission, resulting in insufficient data for analysis. 2.Patients with severe concurrent systemic diseases and an expected survival of less than 3 months (e.g., advanced malignant tumors, end-stage liver or kidney failure). 3.Patients with conditions that significantly affect inflammatory markers, such as active infections, systemic autoimmune diseases, or hematological disorders. 4.Patients with a history of significant neurological deficits that may affect prognosis assessment (e.g., pre-existing mRS score >= 2). 5.Patients with missing or unreliable critical data (e.g., incomplete hematological test results). 6.Patients for whom outcomes could not be assessed due to early discharge following treatment withdrawal. 7.Patients who received specific treatments during the current hospitalization that may affect the study indicators (e.g., investigational drugs, surgeries, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day and 365-day survival status; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU length of stay;Total length of stay; | — |
Countries
China
Contacts
Public ContactDeng Shuixiang
Huashan Hospital, Fudan University
Outcome results
None listed