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Study on the Absorption Rate Verification of HotRule Hexa-Protein Powder and Its Effects and Mechanismson on Human Muscle Gain, Muscle Function, and Exercise Performance

Study on the Absorption Rate Verification of HotRule Hexa-Protein Powder and Its Effects and Mechanismson on Human Muscle Gain, Muscle Function, and Exercise Performance

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118991
Enrollment
Unknown
Registered
2026-02-13
Start date
2026-02-26
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Test group (Study One):A three-phase, randomized, double-blind, crossover controlled design will be employed, with a planned enrollment of 12 subjects. Each subject will receive, in a randomized order
PL group (Study Two):Following each resistance training session, subjects receive an amount of maltodextrin placebo equivalent to that provided to the HotRule Hexa-Protein Powder group.
HotRule group (Study Two):Following each resistance training session, subjects receive 30 g of HotRule Hexa-Protein Powder.

Sponsors

Guangzhou Sport University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 24 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for Study one: (1) Male university students aged 18–24 years. (2) BMI: 18.5–24 kg/m². (3) In good general health with no history of gastrointestinal disorders, hematological diseases, or allergies. Inclusion criteria for Study two: (1) Male university students aged 18–24 years. (2) Had not engaged in systematic resistance training (>= 3 times per week) in the six months prior to the study. (3) Blood pressure <= 140/90 mmHg, free from diagnosed metabolic, cardiovascular, or motor disorders; confirmed to be healthy via a routine medical screening questionnaire; and cleared for exercise participation based on the Physical Activity Readiness Questionnaire (PAR-Q).

Exclusion criteria

Exclusion criteria: Exclusion criteria for Study one: (1) With a history of gastrointestinal or hematological diseases. (2) Allergy to the trial protein or related ingredients. (3) History of supplement or medication use within the past 6 months, or presence of unhealthy habits such as smoking or alcohol consumption. Exclusion criteria for Study two: (1) Presence of underlying medical conditions known to affect muscle metabolism (e.g., diabetes, cardiovascular diseases). (2) Allergy to the trial protein or related ingredients. (3) History of dietary supplement or medication use within the past six months, or engagement in lifestyle habits such as smoking or alcohol consumption.

Design outcomes

Primary

MeasureTime frame
Levels of amino acids in plasma (Study One);Body composition (Study Two);Body circumference (Study Two);Muscle thickness (Study Two);Maximum Muscle Strength (1RM: Bench Press, deep squat) (Study Two) ;Muscular Endurance (Bench Press, deep squat) (Study Two) ;Knee Isokinetic Muscle Strength (Study Two);Exercise performance (RPE, heart rate, vertical jump, standing long jump, triple hop test) (Study Two);

Secondary

MeasureTime frame
Surface myoelectricity (Study Two);Blood indicators (insulin-like growth factor-1, testosterone, glucagon-like peptide-1, vitamin E, vitamin D3, growth hormone, cortisol, lactate dehydrogenase, creatine kinase, myoglobin, urea nitrogen) (Study Two);Bowel reactions (Bowel tolerance questionnaire, bowel habit diary) (Study Two);

Countries

China

Contacts

Public ContactYanlong Niu

School of Sport and Health, Guangzhou Sport University

nyl_csss@126.com+86 130 1126 5822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026