Hysteroscopic
Conditions
Interventions
Oxycodone group:The initial dose of oxycodone for the first patient was 0.1 mg/kg. For subsequent patients, the dose was adjusted based on the response of the immediately preceding patient to oxycodo
if no body movement response occurred, the dose for the next patient was decreased by 0.05 mg/kg.
Sponsors
Women’s Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for hysteroscopic surgery; 2. Aged 18–65 years; 3. With a BMI of 18–25 kg/m^2; 4. ASA physical status class I–II; 5. No severe cardiopulmonary, hepatic or renal diseases; 6. No history of psychiatric disorders; 7. No drug allergies.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with severe cardiovascular, pulmonary, hepatic or renal comorbidities; 3. A history of long-term use of psychotropic, sedative or analgesic medications; 4. Hypersensitivity or contraindications to the study drugs; 5. Documented difficult airway; 6. Current participation in another clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor response during cervical dilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate;Oxygen saturation;Respiratory rate;End-tidal carbon dioxide;Entropy index;Surgical Pleasure Index;Oxycodone dose;Cisplatin dose;Anesthesia recovery time (time from discontinuation of cisplatin infusion to patient's spontaneous eye opening); | — |
Countries
China
Contacts
Public ContactSun Lihong
Women’s Hospital, Zhejiang University School of Medicine
Outcome results
None listed