cervical cancer
Conditions
Interventions
control group:usual care
observation group:Standard care + SSM-driven symptom cluster intervention program
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Women aged between 18 and 75 who signed the informed consent form; 2. Signed informed consent and pathologically confirmed as recurrent and metastatic cervical cancer; 3. The first time to receive chemotherapy, anti-angiogenesis and other combined PD-1/PD-L1 inhibitors or bispecific antibody treatment; 4. Expected survival period >= 6 months; 5. Karnofsky functional status score (Karnofsky Performance Status, KPS) is >= 70 points; 6. Clear consciousness, able to cooperate in completing the SSM-based assessment.
Exclusion criteria
Exclusion criteria: 1. Combine severe autoimmune diseases and mental illnesses; 2. Previous ICI treatment resulted in grade 3 or higher irAEs;; 3. Persons with language/cognitive impairments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes in the severity of symptom clusters ;the improvement in levels of inflammatory factors; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement effect of quality of life;Change in functional status;Severity of adverse events;Interruption rate of treatment; | — |
Countries
China
Contacts
Public ContactYing Wang
Zhejiang Cancer Hospital
Outcome results
None listed