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Effect of Kangfuxin Liquid combined with minocycline and ofloxacin on chronic periodontitis and periodontal inflammation

Effect of Kangfuxin Liquid combined with minocycline and ofloxacin on chronic periodontitis and periodontal inflammation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118944
Enrollment
Unknown
Registered
2026-02-13
Start date
2026-02-16
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic oral periodontitis

Interventions

The control group :Treated with a combination of ofloxacin and minocycline.
The observation group :On top of the treatment given to the control group, Kangfu Xin Ye was added.

Sponsors

Affiliated Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years; 2. In good general health with no other serious complications; 3. Capable of self-care and able to receive treatment in full compliance with the study requirements; 4. Having signed the informed consent form; 5. X-ray examination showing alveolar bone resorption exceeding 1/3 to 1/2 of the root length.

Exclusion criteria

Exclusion criteria: 1. Women who are pregnant or breastfeeding; 2. Those with immunodeficiency, liver or kidney dysfunction, or similar conditions; 3. Individuals allergic to Kangfu New Liquid, minocycline, or any component of ofloxacin; 4. Those who have received related treatments in the past three weeks that may affect the observation indicators; 5. Those who have undergone immunotherapy in the past six months or recently used antibiotics; 6. Individuals with systemic diseases such as hypertension or diabetes that are poorly controlled.

Design outcomes

Primary

MeasureTime frame
Sulcus Bleeding Index (SBI);Gingival Index (GI);Plaque Index (PLI) levels.;

Countries

China

Contacts

Public ContactYumeng Huang

Affiliated Hospital of Jiangsu University

497975942@qq.com+86 183 5285 3027

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026