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A retrospective study on particle radiotherapy for thoracic bone and soft tissue sarcoma

A retrospective study on particle radiotherapy for thoracic bone and soft tissue sarcoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118943
Enrollment
Unknown
Registered
2026-02-13
Start date
2026-02-14
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone and Soft Tissue Sarcoma

Interventions

Sponsors

Shanghai proton and heavy ion center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1) Patients with thoracic bone and soft tissue tumors who received particle radiotherapy at Shanghai Proton and Heavy Ion Hospital; 2) Pathologically confirmed primary thoracic bone and soft tissue tumors, or pathologically confirmed metastatic thoracic bone and soft tissue tumors from a known primary site; 3) Aged >= 14 years; 4) Having at least one follow-up visit, with the follow-up time being at least 1 month after the initiation of radiotherapy.

Exclusion criteria

Exclusion criteria: 1) At the same time, there are uncontrolled malignant tumors that may significantly shorten the expected survival of lung cancer in the patient; 2) Patients with pacemakers, such as high-energy rays that may interfere with the normal function of the pacemaker; If there is a metal prosthesis implant in the body, it may significantly affect the calculation of the target radiation dose; 3) HIV-positive, including prior treatment on antiretroviral therapy; Chronic hepatitis B, viral replication phase; active phase of hepatitis C; active syphilis; 4) have a history of psychiatric illness that may impede the completion of treatment; 5) Have serious comorbidities that may affect the delivery of radiotherapy, including: a) uncontrolled acute inflammation; b) Uncontrolled unstable angina, congestive heart failure, myocardial infarction, cerebral hemorrhage, severe chronic obstructive pulmonary disease and other cardiopulmonary and cerebral diseases, which may lead to treatment risks as assessed by specialists; c) Pregnant or lactating; d) Other diseases that may affect particle therapy; 6) the department discussed that particle radiotherapy would not be able to provide patients with a clear benefit; 7) After repeated communication, they are still unable to understand the purpose of treatment, unable to cooperate with treatment, or unwilling to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Local control rate;

Secondary

MeasureTime frame
Progression-free survival rate;Overall survival rate;

Countries

China

Contacts

Public ContactJingfang Mao, Kai-Liang Wu

Shanghai proton and heavy ion center

jingfang.mao@sphic.org.cn+86 21 3829 6666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 17, 2026