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Effect of High-frequency Transcranial Magnetic Stimulation on arthrogenic Muscle Inhibition after Knee Trauma

Effect of High-frequency Transcranial Magnetic Stimulation on arthrogenic Muscle Inhibition after Knee Trauma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118925
Enrollment
Unknown
Registered
2026-02-12
Start date
2026-02-28
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Trauma

Interventions

Control group:Conventional rehabilitation intervention
Experimental group :Adding a transcranial magnetic stimulation protocol on top of standard rehabilitation interventions

Sponsors

Yuebei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years; 2. Unilateral traumatic knee injury (such as ACL tear, grade III meniscus injury, intra-articular fracture, etc.) undergoing surgical or conservative treatment, currently in the rehabilitation phase (4 weeks to 6 months post-injury/surgery); 3. Quadriceps central activation ratio (CAR) less than 80%; 4. Range of motion (ROM) of the affected knee >= 90° flexion; 5. Able to understand and comply with the study procedures and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Contraindications for rTMS (history of epilepsy, brain surgery/metal implants, severe heart disease, implanted electronic devices, etc.); 2.knee osteoarthritis grade III or higher (Kellgren-Lawrence classification); 3.peripheral nerve or nerve root injury; 4.other severe lower limb injuries or diseases affecting functional assessment (e.g., stroke, spinal cord injury); 5.inability to cooperate with isokinetic muscle strength testing or understand instructions; 6. planning or receiving other new treatments (e.g., botulinum toxin injections) that may significantly affect quadriceps nerve function or muscle strength during the study; 7. pregnant or breastfeeding women; 8.other circumstances deemed unsuitable by the investigator: such as the presence of specific or unstable comorbidities that do not meet explicit exclusion criteria but are considered by the investigator to potentially significantly increase risks; inability to fully understand study requirements due to cognitive impairment, mental status, language or cultural barriers; lack of sufficient willingness or adherence to reliably complete the entire study process; participation or planning of other therapies or programs that may interfere with the study.

Design outcomes

Primary

MeasureTime frame
RMT,Resting Motor Threshold;motor evoked potential;Central Activation Ratio, CAR;Passive Position Matching;AMI Classification;Lysholm knee score;

Secondary

MeasureTime frame
Hamstring/Quadriceps Ratio,H/Q;(Peak Torque, PT);

Countries

China

Contacts

Public ContactLai Feng

Yuebei People's Hospital

laifeng190016@163.com+86 188 2634 7765

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026