Allergic bronchopulmonary aspergillosis
Conditions
Interventions
Training Set:None
Validation Set:None
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Meeting the 2017 Chinese Society of Respiratory Disease, Asthma Group diagnostic criteria for Allergic Bronchopulmonary Aspergillosis (ABPA): 1. Associated disease: Asthma or other conditions such as bronchiectasis, COPD, or cystic fibrosis; 2. Essential criteria: Aspergillus fumigatus-specific IgE > 0.35 kUA/L or positive immediate skin test to Aspergillus fumigatus; serum total IgE level > 1000 IU/mL; 3. Additional criteria: Peripheral blood eosinophil count > 0.5 × 10?/L; radiographic findings consistent with ABPA (including but not limited to transient opacities such as pulmonary consolidation, nodules, "mucus plug" or "finger-in-glove" signs, or migratory shadows; or persistent changes such as bronchiectasis or pleuropulmonary fibrosis); positive serum Aspergillus-specific IgG antibodies or precipitins. Diagnosis of ABPA requires fulfillment of criterion 1, criterion 2, and at least two of the criteria in group 3. If all other criteria are met, ABPA may still be diagnosed even if serum total IgE is 18 years.
Exclusion criteria
Exclusion criteria: 1. Presence of malignancy or severe organ dysfunction (e.g., cardiac, cerebral, or renal failure). 2. Pregnant or lactating women. 3. Incomplete medical records or insufficient diagnostic data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospital mortality rate;Importance of predictor variables in XGBoost model predictions; | — |
Countries
China
Contacts
Public ContactZhang Jing
Yuebei People’s Hospital
Outcome results
None listed