Aromatase Inhibitor-Associated Musculoskeletal Symptoms
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Female breast cancer patients with a pathological diagnosis of hormone receptor-positive stage I-III disease at or prior to enrollment in this study; 2. Currently taking aromatase inhibitors for a duration of >=3 months; 3. Experience significant aromatase inhibitor-associated musculoskeletal symptoms (e.g., pain, stiffness, muscle soreness) persisting for >=3 months following treatment initiation, with a Brief Pain Inventory (BPI) score of >=3 in the past week; 4. Age >=18 years with adequate verbal communication skills; 5. Voluntary participation and ability to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of severe psychiatric disorders or cognitive, hearing, or expressive impairments that preclude cooperation; 2. Presence of pain unrelated to breast cancer, such as other chronic musculoskeletal pain conditions (e.g., rheumatoid arthritis, severe osteoarthritis); 3. Previous participation in similar intervention programs with systematic self-management experience.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brief Pain Inventory , BPI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quick Disabilities of the Arm, Shoulder, and Hand;Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC;Chinese Version of the Self-Efficacy to Manage Chronic Disease Scale, C-SEMCD;Functional Assessment of Cancer Therapy-Breast, FACT-B; | — |
Countries
China
Contacts
Guangdong Medical University