Diaphragmatic Function Impairment
Conditions
Interventions
Group S:Reversal of neuromuscular blockade with Sugammadex Sodium
Group N:Reversal of neuromuscular blockade with Neostigmine
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients Undergoing Elective Non-thoracoabdominal Surgery; 2. Age: 60–80 years; ASA classification = 60 min and <= 180 min; total blood loss <= 5 ml/kg; 4. Patients meeting the diagnostic criteria for sarcopenia.
Exclusion criteria
Exclusion criteria: 1. With severe cardiovascular and cerebrovascular diseases, severe respiratory diseases, severe hepatic and renal dysfunction, severe neuromuscular diseases, or uncontrolled chronic metabolic diseases; 2. With pleuroperitoneal effusion or tumors that affect diaphragmatic function; 3. If the skin at the site of the ultrasound examination is infected or damaged, or if there are other conditions that are not suitable for completing the diaphragm ultrasound examination; 4. With a history of allergy to rocuronium, sugammadex sodium, neostigmine, glycopyrrolate, or other contraindications to the administration of these drugs; 5. As determined by an anesthesiologist, cases where the use of sugammadex sodium or neostigmine for neuromuscular blockade reversal is associated with potential risks or uncertain benefits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm Excursion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pulmonary Complications;Diaphragmatic Thickening Fraction;Time of extubation; | — |
Countries
China
Contacts
Public ContactHuang Lina
Shanghai General Hospital
Outcome results
None listed