Postoperative delirium
Conditions
Interventions
Cognitive Frailty Group:None
Control Group:None
Sponsors
The Second Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years and < 90 years, regardless of sex. 2. Scheduled to undergo non-cardiac surgery under neuraxial anesthesia. 3. American Society of Anesthesiologists (ASA) physical status classification I~III. 4. Voluntary participation with a signed informed consent form. 5. Complete clinical data and ability to complete follow-up assessments.
Exclusion criteria
Exclusion criteria: 1. Dementia. 2. Inability to communicate preoperatively due to coma, or severe visual/hearing/language impairment. 3. Pre-existing conditions: schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis. 4. Severe dysfunction of the heart, brain, kidney, or liver; or history of severe craniocerebral injury. 5. Patients scheduled for emergency surgery or intracranial surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium within 3 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative CSF Proteomic and Metabolomic Profiles;QoR-15 Score within 3 days after surgery;Incidence of postoperative adverse events within 3 days after surgery;Preoperative SCD Scale Score;Preoperative HADS Score;Preoperative PSQI Score; | — |
Countries
China
Contacts
Public ContactMuhuo Ji
The Second Affiliated Hospital of Nanjing Medical University
Outcome results
None listed