rheumatoid arthritis cardiovascular disease
Conditions
Interventions
Normal group:None
Rheumatoid arthritis low activity group group (Rheumatoid activity classification, DAS-28 score 5.1):None
Sponsors
Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. RA Diagnostic Criteria: Meet the RA diagnostic criteria proposed by the American College of Rheumatology (ACR) in 1987, or the RA classification criteria jointly established by the ACR and the European League Against Rheumatism (EULAR) in 2010. 2. Age 18–70 years, any gender. 3. The patient is informed and consents to participate in this study. 4. Normal control group: Select healthy volunteers matched with RA patients in age and gender.
Exclusion criteria
Exclusion criteria: 1.Patients with severe end-stage organ failure, hematologic diseases, malignant tumors, or psychiatric disorders; 2.Patients with other systemic autoimmune diseases (such as ankylosing spondylitis, systemic lupus erythematosus, Sjögren's syndrome, systemic vasculitis, dermatomyositis, etc.); 3.Patients with congenital heart disease (such as atrial septal defect, ventricular septal defect, patent ductus arteriosus, tetralogy of Fallot, etc.); 4.Patients previously diagnosed with the following severe cardiovascular diseases: severe arrhythmias (such as persistent atrial fibrillation, malignant ventricular arrhythmias, etc.), or structural heart disease (such as severe valvular heart disease, hypertrophic or dilated cardiomyopathy, etc.); 5.Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global Longitudinal Strain;Arterial velocity-pulse index;Arterial pressure-volume index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic Blood Pressure;arterial pulse pressure;28-joint Disease Activity Score; | — |
Countries
China
Contacts
Public ContactLin Jin
Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed