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Association Between Early Postoperative Oxygen Partial Pressure Exposure and Graft Function Recovery in Adult Liver Transplant Recipients: A Retrospective Cohort Study

Association Between Early Postoperative Oxygen Partial Pressure Exposure and Graft Function Recovery in Adult Liver Transplant Recipients: A Retrospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118877
Enrollment
Unknown
Registered
2026-02-12
Start date
2026-02-12
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver transplantation

Interventions

Normal group:None
Hyperoxia group:None
Hypoxia group:None

Sponsors

The Third Affiliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Post-allogeneic liver transplantation; 2.Age > 18 years; 3.Postoperative blood gas analysis =3 times per day for 3 days;

Exclusion criteria

Exclusion criteria: 1.Re-transplantation within 7 days postoperatively; 2.Combined organ transplantation (e.g., liver-kidney, liver-heart combined transplantation); 3.Missing rate of critical data =30% (Definition of critical data: PaO2 during the first 3 postoperative days, all laboratory indicators required for EAD diagnosis, and core confounding factors [recipient age, MELD score, cold ischemia time, operative time, surgical complications, graft quality]);

Design outcomes

Primary

MeasureTime frame
Incidence of early allograft dysfunction;

Secondary

MeasureTime frame
30-day mortality;Length of ICU stay;Total length of hospital stay;

Countries

China

Contacts

Public ContactLv Haijin

The Third Affiliated Hospital Sun Yat-sen University

lvhaijin@mail.sysu.edu.cn+86 20 85252672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026