None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: Age 18 to 65 years 2: Healthy volunteers, voluntarily participated in the experiment and signed the informed consent form; 3: No history of neurological chronic disease; 4: No history of craniocerebral or spinal cord trauma or surgery 5: No claustrophobia 6: No sleep apnea syndrome; 7: ASAI-II;18 kg/m2<BMI<30 kg/m^2;
Exclusion criteria
Exclusion criteria: 1: Those who are unable to cooperate in completing the scale assessment; 2: Those who have metal implants in their bodies or are unable to complete the MRI examination for other reasons; 3: Those allergic to remimazolam besylate or drug ingredients; 4: Pregnant and lactating women 5: Participated in other clinical researchers within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Verbal fluency including phonemic and semantic fluency was evaluated through the Verbal Fluency Test (VFT);Beck Anxiety Inventory (BAI);3DT1-weighted Magnetic Resonance lmaging;Trail Making Test ,TMT;Blood Oxygenation Level Dependent Magnetic Resonance lmaging;Digit Symbol Coding Task (DSC);Wechsler Memory Scale Logical Memory (WMS LM)instant;Wechsler Memory Scale Logical Memory (WMS LM)delay recall;Patient Health;Pain simulation rating.;Headache Impact Test;Mini-Mental State Examination (MMSE);Insomnia Severity Index Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diffusion Tensor imaging(DTI);rial Spin Labeling Magnetic Resonance lmaging; | — |
Countries
China
Contacts
Shaanxi Ankang Central Hospital