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Study on the changes and mechanisms of brain function before and after remazolam anesthesia based on multi-modal magnetic resonance

Study on the changes and mechanisms of brain function before and after remazolam anesthesia based on multi-modal magnetic resonance

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118864
Enrollment
Unknown
Registered
2026-02-11
Start date
2026-02-12
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Observation group:None

Sponsors

Shaanxi Ankang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1:   Age 18 to 65 years 2:   Healthy volunteers, voluntarily participated in the experiment and signed the informed consent form; 3:   No history of neurological chronic disease; 4:   No history of craniocerebral or spinal cord trauma or surgery 5:   No claustrophobia 6:   No sleep apnea syndrome; 7:   ASAI-II;18 kg/m2<BMI<30 kg/m^2;

Exclusion criteria

Exclusion criteria: 1:   Those who are unable to cooperate in completing the scale assessment; 2:   Those who have metal implants in their bodies or are unable to complete the MRI examination for other reasons; 3:   Those allergic to remimazolam besylate or drug ingredients; 4:   Pregnant and lactating women 5:   Participated in other clinical researchers within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Verbal fluency including phonemic and semantic fluency was evaluated through the Verbal Fluency Test (VFT);Beck Anxiety Inventory (BAI);3DT1-weighted Magnetic Resonance lmaging;Trail Making Test ,TMT;Blood Oxygenation Level Dependent Magnetic Resonance lmaging;Digit Symbol Coding Task (DSC);Wechsler Memory Scale Logical Memory (WMS LM)instant;Wechsler Memory Scale Logical Memory (WMS LM)delay recall;Patient Health;Pain simulation rating.;Headache Impact Test;Mini-Mental State Examination (MMSE);Insomnia Severity Index Scale;

Secondary

MeasureTime frame
Diffusion Tensor imaging(DTI);rial Spin Labeling Magnetic Resonance lmaging;

Countries

China

Contacts

Public ContactXiao hui

Shaanxi Ankang Central Hospital

171987535@qq.com+86 185 0915 0059

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026