Periodontitis
Conditions
Interventions
Patients with periodontitis accompanied by inflammatory bowel disease in active period:None
Patients with periodontal health accompanied by inflammatory bowel disease in active period:None
Patients with periodontitis and without inflammatory bowel disease:None
Sponsors
Stomatology Hospital,Zhejiang University School Medicine
Eligibility
Sex/Gender
All
Age
16 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age greater than 16 years and less than 75 years. 2.Diagnosis of Crohn's disease or ulcerative colitis confirmed clinically, endoscopically, or pathologically. 3.3. Inflammatory bowel disease in either an active or remission stage. (Definition of Active Disease: Crohn's Disease: Harvey-Bradshaw Index (HBI) >= 5 ,Ulcerative Colitis: Partial Mayo (pMayo) Score >= 2, with no single subscore > 2);
Exclusion criteria
Exclusion criteria: 1.Having received periodontal non-surgical treatment within the past 3 months. 2.Have used antibiotics within the past 3 months. 3.Diagnosis of diabetes mellitus. 4.Presence of severe concomitant diseases affecting the cardiac, pulmonary, or hematopoietic systems; current pregnancy; or history of surgery within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical loss of attachment; | — |
Secondary
| Measure | Time frame |
|---|---|
| bleeding on probing;Metabolomics analysis;Periodontal probing depth;Microbial community structure of sequencing of the 16S RNA gene;Tooth mobility; | — |
Countries
China
Contacts
Public ContactFeifei Mao
Stomatology Hospital,Zhejiang University School Medicine
Outcome results
None listed