Postoperative cesarean section patients
Conditions
Interventions
experimental group:Experimental group: At the end of surgery, when closing the abdomen to the subcutaneous fascia layer, 266mg of bupivacaine liposomes (diluted to 40ml with 0.9% sodium chloride solut
control group:Control group: 150mg of bupivacaine (diluted to 40ml with 0.9% sodium chloride solution) was administered during the same period for local infiltration anesthesia at the incision site us
Sponsors
Ningjin County People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult parturients aged >= 18 years old; 2. American Society of Anesthesiologists (ASA) classification I-II; 3. Single pregnancy, gestational age >= 37 weeks (full-term); 4. Perform elective or emergency cesarean section surgery; 5. Voluntarily participate in this study, fully understand the research content, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergic to amide local anesthetics; 2. Severe complications during pregnancy (such as severe preeclampsia, HELLP syndrome, placental abruption and massive bleeding, etc.); 3. Severe liver and kidney dysfunction; 4. Long term use of opioid analgesics or drug abuse; 5. There is active infection at the surgical incision site; 6. Cognitive impairment, unable to cooperate with pain assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the NRS score curve for resting pain within 72 hours after surgery (AUC);Cumulative total opioid consumption (milligrams of morphine equivalent, MUC) within 0-72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores during rest and activity at each time point;First pain relief time;Opioid consumption at different time periods;patient satisfaction;First time getting out of bed after surgery;Intestinal function recovery time;First successful breastfeeding time;length of hospital stay; | — |
Countries
China
Contacts
Public ContactZhigang Zhang
Ningjin County People's Hospital
Outcome results
None listed