Postoperative analgesia for elderly patients undergoing hip replacement surgery
Conditions
Interventions
Group A (exposure group):The PCA pump drug used in Group A is hydromorphone. The formula is hydromorphone 0.2mg/kg+ondansetron 16mg+physiological saline diluted to 100ml. Parameters: background dose 2
Group B (control group):Group B used PCA pump drug sufentanil. Formula: Sufentanil 2 µ g/kg+ondansetron 16mg+diluted with physiological saline to 100ml. Parameters: background dose 2ml/h, single compr
Sponsors
Ningjin County People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 65 years old; 2. American Society of Anesthesiologists classification I-III; 3. Planned elective unilateral primary total hip replacement surgery; 4. Voluntarily participate and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Known allergy to opioids (hydromorphone, sufentanil) or contraindications to their use; 2. Severe liver or kidney dysfunction; 3. Long-term chronic use of opioids or history of substance abuse; 4. Severe cognitive impairment, mental illness, or inability to communicate, making pain assessment impossible; 5. Surgical site infection or coexisting neurological disorders affecting functional assessment; 6. Intraoperative switch to other analgesic regimens or occurrence of serious complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rest and activity VAS scores at 6h, 12h, 24h, and 48h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total opioid dosage within 48 hours after surgery;PCA compression frequency (effective compression/total compression);First time getting out of bed;Harris hip score at 1 week/1 month/3 months after surgery;length of hospital stay; | — |
Countries
China
Contacts
Public ContactYali Wang
Ningjin County People's Hospital
Outcome results
None listed