Neurobehavioral development of premature infants
Conditions
Interventions
High-proportion breastfeeding group:None
The medium proportion breastfeeding group:None
Low-proportion breastfeeding group:None
Sponsors
Huzhou Maternity & Child Health Care Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Preterm infants hospitalized in the NICU of a municipal hospital from January 2026 to July 2026. 1. Birth gestational age =26 weeks, and/or birth weight =600 g, with complete clinical data; 2. Age at admission =7 d; 4. No intrauterine infection, no use of probiotics; 5. Maternal prenatal antibiotic use <7 days; 6. Regular follow-up as required; 7. Informed consent signed by guardians.
Exclusion criteria
Exclusion criteria: 1. Having diseases such as hypoxic-ischemic encephalopathy, bilirubin encephalopathy, epilepsy, central nervous system infection, abnormal brain development or malformation confirmed by MRI, and definite craniocerebral trauma; 2. Having congenital malformations, congenital immunodeficiency diseases, severe heart diseases, and congenital inborn errors of metabolism; 3. Apgar score < 3 at 1 minute after birth; 4. Infants who voluntarily discharged from hospital or died within 1 week; 5. Incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurobehavioral Developmental Clinical Outcomes in Preterm Infants;Gut Microbiota and Its Metabolites Profile; | — |
Countries
China
Contacts
Public ContactSong Xuhong
Huzhou Maternity & Child Health Care Hospital
Outcome results
None listed