None
Conditions
Interventions
Experimental group:Anesthesia and sedation were achieved during the operation using propofol.
Control group:Anesthesia and sedation were achieved during the operation through the use of propofol.
Sponsors
The People's Hospital of Leshan
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing elective painless gastroscopy and colonoscopy; 2.Age range: 18 - 65 years old. Gender: No restrictions. 3.Body Mass Index (BMI): 18.5 - 28 kg/m^2; 4.American Society of Anesthesiologists Classification (ASA): I - III grades; 5.The operation time is within 1 hour. 6.The subjects voluntarily participated in this trial and signed the informed consent form for this trial.
Exclusion criteria
Exclusion criteria: 1.Those who have a history of allergic reactions to opioid drugs, etomidate, propofol, and naloxone excipients; 2.Using beta-blockers, anti-anxiety drugs, and antidepressants; 3.Those suspected of abusing narcotic painkillers or sedatives, as well as alcoholics; 4.Electrocardiogram indication: Heart rate 100 beats/min or with severe arrhythmia; 5.A history of acute respiratory infection within the past two weeks that has not been cured; 6.Patients with mental illnesses who cannot cooperate; 7.For patients with preoperative hypertension, if their systolic blood pressure is greater than 180 mmHg and/or their diastolic blood pressure is greater than 110 mmHg, or for patients with hypotension, if their blood pressure is less than 90/60 mmHg; 8.Those who have a history of abnormal anesthesia recovery from previous surgeries; 9.Predicting patients with potential or actual difficult airways, such as those classified as grade III-IV according to the modified Mallory classification system; 10.Pregnant or lactating women; 11.Other researchers believe that other participants who were not suitable for this study were excluded; 12.The subject explicitly refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Check time, wake-up time, wake-up time to leave PACU;The proportion of successful operations;Anesthetic effect;Adverse reactions (nausea, vomiting, etc.);Satisfaction score; | — |
Countries
China
Contacts
Public ContactLin Hongyan
The People's Hospital of Leshan
Outcome results
None listed