Hepatocellular carcinoma
Conditions
Interventions
Post-hepatectomy patient cohort:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients in generally good condition; 2. American Society of Anesthesiologists (ASA) physical status classification of I/II; 3. Preoperative liver function assessed as Child-Pugh class A; 4. Indocyanine green retention rate at 15 minutes (ICG R15) =3 liver segments; 6. Negative surgical margin.
Exclusion criteria
Exclusion criteria: 1.Presence of severe liver cirrhosis or steatohepatitis; 2.Use of anti-inflammatory medications within 2 weeks prior to surgery; 3.Postoperative receipt of chemotherapy, targeted therapy, or immunotherapy; 4.Recurrent hepatocellular carcinoma requiring a second or multiple hepatectomies; 5.Concurrent resection of other organs; 6.History of other malignancies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative liver regeneration volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma 4-hydroxyderricin concentration;Hepatic tissue 4-hydroxyderricin concentration;Demographic and clinical characteristics including age, sex, comorbidities, postoperative complications, hospital stay duration, and survival time; | — |
Countries
China
Contacts
Public ContactZeng Yong
West China Hospital of Sichuan University
Outcome results
None listed