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Study on the Effects of Tranexamic Acid on Postoperative Delirium in Elderly Patients Undergoing Hip Replacement and Its Inflammatory Mechanisms

Study on the Effects of Tranexamic Acid on Postoperative Delirium in Elderly Patients Undergoing Hip Replacement and Its Inflammatory Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118722
Enrollment
Unknown
Registered
2026-02-10
Start date
2026-02-17
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

TXA Group:none
No tranexamic acid usage group:none

Sponsors

The First Hospital of Jiaxing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>= 65 years; 2. Undergoing hip or knee joint replacement surgery; 3. ASA grade I to III; 4. All anesthesia methods were general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Having central nervous system infections, stroke, head trauma, epilepsy, multiple sclerosis or other major neurological disorders; 2. Having severe psychological conditions such as depression or long-term use of psychotropic drugs, steroid drugs and hormone drugs; 3. Having cognitive dysfunction such as delirium or dementia before the surgery; 4. Having undergone major surgery within the past 1 year; 5. Having incomplete case data or failing to complete follow-up on time.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium incidence;—

Countries

China

Contacts

Public ContactDeng Kang

The First Hospital of Jiaxing

jxmzdk@126.com+86 137 3644 6844

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026