Postoperative pulmonary complications
Conditions
Interventions
Group A:During general anesthesia with mechanical ventilation, the ventilation mode is set to volume-controlled ventilation (VCV). A tidal volume (VT) of 7 ml/kg of ideal body weight is used throughou
Group B:During general anesthesia with mechanical ventilation, the ventilation mode was set to volume-controlled ventilation (VCV), using a tidal volume of 7 ml/kg (ideal body weight), 5 cmH2O PEEP, a
Group C:During general anesthesia with mechanical ventilation, the ventilation mode is set to volume-controlled ventilation (VCV). Throughout the procedure, VT is 7 ml/kg (ideal body weight) with 5 cm
Group D:During general anesthesia with mechanical ventilation, the ventilation mode was set to volume-controlled ventilation (VCV) throughout the procedure, using a tidal volume (VT) of 7 ml/kg (ideal
Sponsors
The Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) class I to III; 2. Aged 18 to 65 years (inclusive); 3. Patients undergoing laparoscopic cholecystectomy, appendectomy, or herniorrhaphy
Exclusion criteria
Exclusion criteria: 1. Refusal of participation by the patient; 2. American Society of Anesthesiologists (ASA) class > ?; 3. Body mass index (BMI) >= 30 kg/m²; 4. Emergency surgery; 5. A history of thoracic surgery within the recent 6 months; 6. Preoperatively known severe cardiac diseases, including but not limited to severe valvular heart disease, severe cardiomyopathy, severe coronary artery stenosis, a history of unstable angina pectoris, severe cardiac insufficiency (New York Heart Association (NYHA) functional class ? or ?), etc; 7. Preoperative comorbidity of chronic pulmonary diseases, including but not limited to chronic obstructive pulmonary disease (COPD), bronchiectasis, asthma, multiple pulmonary bullae or a single pulmonary bulla > 3 cm in diameter, interstitial pneumonia, cor pulmonale, etc; 8. Preoperative comorbidity of severe hypoproteinemia, hypoxemia, hemoglobin (Hb) < 80 g/L, or thoracic/vertebral spinal deformities affecting ventilation; 9. A history of mental illness or cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of atelectasis within 3 days after surgery;Severity of atelectasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung ultrasound score;Postoperative pulmonary complications(PPCs);Intraoperative respiratory mechanics parameters;Intraoperative hemodynamics;PACU length-of-stay;the time of patient with intubation post-operation;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactZhenwei Zheng
The Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed