Renal failure
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Stable dialysis more than 3 months 2.Age from 18 to 80 years 3.If they have cardiovascular diseases, they can receive standardized treatments such as antiplatelet therapy, ACEI/ARB, CCB, etc. 4.Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.An acute cardiovascular or cerebrovascular event occurred within 3 months during the screening period 2.Active infection 3. Patients in the active phase of liver disease with abnormal liver function (ALT or AST levels more than 2.5 times the upper limit of normal) or a history of liver cirrhosis 4.A history of cardiac surgery within 3 months prior to screening 5.Detection of malignant tumors within 3 months prior to screening, or undergoing radiotherapy/chemotherapy 6.A life-threatening severe infection occurred within 3 months prior to screening 7.Enrollment in other clinical research projects within 3 months prior to screening 8.Pregnant and lactating women, or patients using estrogen replacement therapy 9.Patients with active infectious diseases, such as active tuberculosis or HIV infection 10.Patients with psychiatric disorders who are taking psychotropic medications 11.The patient is deemed by the physician to be unlikely to follow up or to have poor compliance, and thus is not suitable for enrollment. 12. Patients who are unwilling to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events; | — |
Secondary
| Measure | Time frame |
|---|---|
| soluble Suppression of Tumorigenicity 2,B-type Natriuretic Peptide change;All Cause Death;dialysis techneq failure;Residual renal function; | — |
Countries
China
Contacts
Shanghai East Hospital