Erythematotelangiectatic rosacea (ETR)
Conditions
Interventions
Transcutaneous auricular vagus nerve stimulation group:Transcutaneous auricular vagus nerve stimulation
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged between 18 and 60 years (inclusive, with no gender restrictions); 2. Meeting the diagnostic criteria for erythematous telangiectatic rosacea and having a CEA score of 2 or higher; 3. Capable of adhering to the study or follow - up procedures, and collaborating in observing adverse events and therapeutic effects; 4. The patient's voluntary participation in the study and signing of a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Subjects diagnosed with papulopustular, ocular, or rhinophymatous rosacea; 2. Subjects with a CEA score lower than 2; 3. Subjects who have participated in any drug or non - drug clinical research within one month before enrollment; 4. Subjects with bradycardia, severe diseases of important organs (e.g., heart, liver, lungs, and kidneys), hematological disorders, or other diseases that the investigator considers unsuitable for participation in the clinical trial; 5. Subjects with malignant tumors, systemic failure, or low immune function; 6. Subjects with concurrent facial acne, atopic dermatitis, hormone - dependent dermatitis, or other facial skin - related diseases; 7. Subjects with a history of epilepsy, a family history of epilepsy, tic disorders, or other mental and neurological disorders that impede cooperation; 8. Subjects with abscesses, infections, ulcers, edema, or scars on the auricle skin; 9. Subjects who are unwilling or unable to cooperate for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinician’s Erythema Assessment score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire–9;Global Flushing Severity Scale;Generalized Anxiety Disorder–7;Facial Itch Numerical Rating Scale;Patient Self- Assessment score; | — |
Countries
China
Contacts
Public ContactJian Li
The First Affiliated Hospital of Army Medical University
Outcome results
None listed