femoral neck fracture
Conditions
Interventions
0.2 mg epinephrine group:The dose of adrenaline in the cocktail was 0.2 mg.
0.3 mg epinephrine group:The dose of adrenaline in the cocktail was 0.3 mg.
0.4 mg epinephrine group:The dose of adrenaline in the cocktail was 0.4 mg.
0.5mg epinephrine group:The dose of adrenaline in the cocktail was 0.5 mg.
Sponsors
Yuyao Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years old and <= 99 years old ; 2. Garden type III or IV femoral neck fracture was diagnosed by X-ray or CT. 3. Plan to perform primary and unilateral total hip arthroplasty within 72 hours after injury ; 4. American Society of Anesthesiologists grade I-III ; 5. Patients or their legal representatives informed consent, and voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pathological fracture or combined with ipsilateral acetabular, femoral shaft and other serious fractures ; 2. Have a history of ipsilateral hip surgery ; 3. known to be allergic to research drugs ( ropivacaine, compound betamethasone, epinephrine ) or opioids ; 4. Uncontrolled severe systemic diseases ( such as uncontrolled hypertension, coronary heart disease, heart failure, severe arrhythmia, liver and kidney failure ) ; 5. There was a clear history of neurological, mental illness or Alzheimer 's disease before surgery, which could not cooperate with postoperative evaluation ( such as schizophrenia, etc. ) ; 6. Preoperative long-term use of opioids ( > 30 mg / day oral morphine equivalent for > 3 months ) or glucocorticoids ; 7. Active infection or sepsis ; 8. The researchers judged that it was not appropriate to participate in any other situation of this study ( such as the expected survival period < 1 year ).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid drug consumption;Postoperative pain level;perioperative bleeding;inflammatory markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| First landing time;First walking distance; | — |
Countries
China
Contacts
Public ContactQiyuan Lu
Yuyao Hospital of Traditional Chinese Medicine
Outcome results
None listed