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Effects of Short-Term Exposure to Simulated High-Temperature and High-Humidity Environments on Energy Metabolism in Athletes: A Crossover Study

Effects of Short-Term Exposure to Simulated High-Temperature and High-Humidity Environments on Energy Metabolism in Athletes: A Crossover Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118675
Enrollment
Unknown
Registered
2026-02-10
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heat stress

Interventions

Hot–humid followed by thermoneutral condition:Participants initially underwent short-term exposure to a hot and humid environment, followed by a transition to a thermoneutral environment.
Thermoneutral followed by hot-humid condition:Participants were first exposed to a thermoneutral environment for a short period, followed by exposure to a hot and humid environment.

Sponsors

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 30 Years

Inclusion criteria

Inclusion criteria: (1) Body mass index (BMI) between 16 and 28 kg/m^2; (2) Age between 16 and 30 years; (3) No metabolic diseases (e.g., diabetes mellitus, hypertension, etc.); (4) No recent history of surgery, trauma, or major illness; (5) No long-term use of medications affecting energy metabolism, such as hormonal agents, weight-loss drugs, or antidiabetic medications.

Exclusion criteria

Exclusion criteria: (1) Physical limitations (e.g., musculoskeletal injury, osteoarticular disease, or pain); (2) Known serious diseases, including cardiovascular, cerebrovascular, hepatic, or renal disorders; (3) Exercise-related dyspnea; (4) Known family history of sudden death; (5) Known coronary artery disease; (6) Untreated endocrine disorders; (7) Blood pressure >=160/100 mmHg; (8) Use of medications affecting metabolism or cardiovascular function within the past year; (9) Smoking or alcohol consumption exceeding 140 g/week (men) or 70 g/week (women); (10) Inability to adhere to the training protocol during the study period.

Design outcomes

Primary

MeasureTime frame
Energy metabolism (energy expenditure, carbohydrate and fat oxidation);

Secondary

MeasureTime frame
Changes in blood biochemical markers: blood glucose, blood lipids, lactate, hormones, and other indicators;Changes in physiological parameters: heart rate, blood pressure, blood oxygen saturation, heart rate variability, etc.;Subjective questionnaires;Sweat electrolytes;Body temperature (skin and core);Urinary metabolites;Multi-omics profiling;

Countries

China

Contacts

Public ContactGuang Ning

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

guangning@medmail.com.cn+86 183 5910 3009

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026