Skip to content

Effect of High-Flow Nasal Cannula Oxygenation on Hypoxia During Sedated Bronchoscopy in Pediatric Patients: A Multicenter Randomized Controlled Trial

Effect of High-Flow Nasal Cannula Oxygenation on Hypoxia During Sedated Bronchoscopy in Pediatric Patients: A Multicenter Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118659
Enrollment
Unknown
Registered
2026-02-09
Start date
2026-02-09
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoxia

Interventions

Regular Nasal Cannula group:Regular Nasal Cannula
High-flow nasal cannula oxygenation group:High-flow nasal cannula oxygenation

Sponsors

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Age between 1 year and 6 years; 2. Weight >= 10 kg; 3. Scheduled for painless bronchoscopy diagnosis and treatment; 4. Estimated treatment time <= 45 minutes; 5. Obtained written informed consent from the subject's guardian.

Exclusion criteria

Exclusion criteria: 1. SpO2 less than 95% while breathing air; 2. Undergoing sedation and tracheal intubation; 3. Known to have experienced pneumothorax in the past, known to have congenital or acquired upper airway malformations (such as abnormal structures in the nasopharynx), and a history of difficult airway; 4. Having coagulation disorders or a tendency for oral or nasal bleeding, mucosal injury or occupation; 5. Having severe cardiac insufficiency (= IV; 6. Allergic to propofol and sufentanil drugs; 7. Having multiple traumas; 8. Currently participating in other clinical trials; 9. Patients considered by the researcher to be unsuitable for this trial.

Design outcomes

Primary

MeasureTime frame
Hypoxemia (75% <= SpO2 < 90%, lasting < 60 s);

Secondary

MeasureTime frame
Subclinical respiratory Depression(90%=60s);

Countries

China

Contacts

Public ContactDiansan Su

The FIrst Affiliated Hospital, College of Medicine, Zhejiang University

184872238@qq.com+86 571 8723 6249

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026