Depression
Conditions
Interventions
Case group:None
Healthy control group:None
Sponsors
Shandong Mental Health Centre
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients in the clinical research group: 1. Age between 18 and 60 years old; 2. Signed the informed consent form; 3. Met the DSM-5 criteria for Major Depressive Disorder (MDD); 4. HAMD-17 score >= 14 points; 5. Patients who have not received treatment for the current depressive episode within the last 14 days; 6. No self-harm behavior in the past 14 days; 7. Completed primary education or above, able to understand the content of the scale; 8. Comprehended and voluntarily participated in this study, and either the individual or the legal guardian signed the informed consent form. Inclusion criteria for healthy controls in the clinical research group: 1. Age between 18 and 60 years old; 2. Signed the informed consent form; 3. In good health; 4. Completed primary education or above, able to understand the content of the scale; 5. Comprehended and voluntarily participated in this study, and either the individual or the legal guardian signed the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients in the clinical research group: 1. Currently or previously suffering from any diagnosis other than Major Depressive Disorder (MDD as per DSM-5); 2. Having severe or unstable diseases in cardiovascular, liver, kidney, endocrine and metabolic, or nervous system systems; 3. Pregnant or lactating women; 4. Those who have participated in an intervention-based clinical trial within the past 3 months; 5. Those judged by the researchers to have poor compliance or are not suitable for participation. Exclusion criteria for healthy controls in the clinical research group: 1. Currently or previously suffering from any diagnosis as per DSM-5; 2. Having severe or unstable diseases in cardiovascular, liver, kidney, endocrine and metabolic, or nervous system systems; 3. Pregnant or lactating women; 4. Those who have participated in an intervention-based clinical trial within the past 3 months; 5. Those judged by the researchers to have poor compliance or are not suitable for participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differentially expressed gene; | — |
Countries
China
Contacts
Public ContactLi Xiaojing
Shandong mental health center
Outcome results
None listed