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Exploring the relationship between alterations in nasal mocrobiota and the onset and development of depression

Research on the Correlation Between Alterations in Nasal Microbiota and the Onset and Progression of Depression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600118651
Enrollment
Unknown
Registered
2026-02-09
Start date
2026-02-15
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Control group:none
Depression group:none

Sponsors

Tongde Hospital of Zhejiang Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Age between 14 and 60; 2.No antidepressant treatment history; 3.No previous history of upper respiratory tract diseases; 4.Participants and my immediate family members have no history of other mental illnesses (such as schizophrenia, bipolar disorder, etc.), and can complete the questionnaire and related examinations. 5.No history of systemic diseases, such as thyroid dysfunction, diabetes, hypertension, tumors, not in lactation, pregnancy. 6.Agree to participate in this study and sign the informed consent form;

Exclusion criteria

Exclusion criteria: 1.Agree to participate in this study and sign the informed consent form; 2.previous history of upper respiratory tract diseases; 3.Antidepressant medications were administered within the past 3 months; 4.Antibiotics were administered within the past 1 month; 5.history of systemic diseases; 6.Unable or refusing to complete the questionnaire and related examinations; 7.Lost to follow-up or refusal to cooperate;

Design outcomes

Primary

MeasureTime frame
nasal microbiota;Depression/anxiety ;

Secondary

MeasureTime frame
Serological indicators;Olfactory indicators;Cranial imaging indicators;

Countries

China

Contacts

Public ContactLei Chenyang

Tongde Hospital of Zhejiang Province

1335127141@qq.com+86 571 8997 2367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026