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Clinical application study of reversible thyroplasty for the treatment of unilateral vocal cord paralysis

Clinical application study of reversible thyroplasty for the treatment of unilateral vocal cord paralysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118635
Enrollment
Unknown
Registered
2026-02-09
Start date
2026-02-17
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral vocal cord paralysis

Interventions

Experimental group:Reversible thyroplasty

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18–75 years old. 2.Diagnosed through clinical and laryngeal examination as unilateral vocal cord paralysis, with a duration of the condition exceeding 6 months (conservative treatment ineffective). 3.There is a persistent, noticeable voice impairment, and the patient has a strong desire for improvement. 4.The width of the vocal cord fissure is consistent with indications for surgical intervention.

Exclusion criteria

Exclusion criteria: 1.Bilateral vocal cord paralysis; 2.History of previous laryngeal surgery, radiotherapy, or structural abnormalities due to trauma; 3.With severe cardiopulmonary disease, coagulation disorders and other surgical contraindications; 4.Women who are pregnant or breastfeeding; 5.There is cognitive impairment and inability to cooperate in completing follow-up assessments.

Design outcomes

Primary

MeasureTime frame
Improvement rate of glottis closure;

Secondary

MeasureTime frame
Voice Disorder Index ;acoustic indicators;

Countries

China

Contacts

Public ContactYang Hui

West China Hospital, Sichuan University

yh8806@163.com+86 189 8060 1418

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026