End-Stage Renal Disease (ESRD)
Conditions
Interventions
Amino Acid Dialysis Group:Amino Acid (15) Peritoneal Dialysis Solution
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years, undergoing peritoneal dialysis treatment for >=6 months; 2. Serum albumin level 1 year; 6. Good compliance and willingness to sign the informed consent form; 7. Diagnosed with end-stage renal disease (ESRD) with estimated glomerular filtration rate (eGFR) < 15 mL/ (min·1.73 m²).
Exclusion criteria
Exclusion criteria: 1. Hypersensitivity to Amino Acid (15) Peritoneal Dialysis Solution or any of its components; 2. Hepatic dysfunction (ALT/AST >= 2 times the upper limit of normal); 3. Taking medications that affect protein metabolism and unable to maintain a stable dose during the study; 4. Need for adjustment of nutritional supplement doses during the study; 5. Uncorrectable severe gastrointestinal reactions; 6. Pregnant, lactating, or planning to undergo kidney transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nutritional status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Prealbumin, Transferrin, Plasma and PD Ultrafiltrate Amino Acid Profile;Total Urea Clearance Index, Peritoneal Creatinine Clearance;Lean Body Mass;Subjective Global Assessment (SGA) Score; | — |
Countries
China
Contacts
Public ContactWen Xue
Shanghai Tenth People's Hospital
Outcome results
None listed