Chronic ankle instability
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Cross-sectional study participants-Healthy Population Group (Control Group): (1) Aged 18–60 years; (2) No history of ankle sprain or symptoms of chronic ankle instability; (3) No musculoskeletal disorders of the lower limbs (e.g., arthritis, hip/knee pathologies, surgical history); (4) No severe visual impairment that would interfere with testing using stroboscopic glasses; (5) No neurological diseases or cognitive impairments; (6) Able to follow verbal instructions and provide signed informed consent. Cross-sectional study participants-CAI Group (Case Group): (1) Patients diagnosed with chronic ankle instability according to the International Ankle Consortium criteria, with a clear history of recurrent ankle sprains (initial sprain occurring at least 12 months prior to enrollment, and the most recent sprain at least 3 months prior to enrollment); the ankle has experienced at least two episodes of "giving way" or "feeling unstable" in the past 6 months; preliminary screening using the Cumberland Ankle Instability Tool (CAIT), with participants scoring =24 points; (2) Aged 18–60 years; (3) No severe visual impairment that would interfere with the use of stroboscopic glasses; (4) Able to follow verbal instructions and provide signed informed consent. Participants of the randomized controlled study: (1) Patients diagnosed with chronic ankle instability according to the International Ankle Consortium criteria, with a clear history of recurrent ankle sprains (the initial sprain occurring at least 12 months before enrollment, and the most recent sprain at least 3 months before enrollment); the ankle has experienced at least two episodes of "giving way" or "feeling of instability" in the past 6 months; preliminary screening using the CAIT, with participants scoring =24; (2) Aged 18–60 years; (3) No severe visual impairment that would interfere with the use of stroboscopic glasses; (4) Able to follow verbal instructions and provide signed informed consent.
Exclusion criteria
Exclusion criteria: Cross-sectional study participants-Healthy Population Group (Control Group): (1) Acute injury to the lower limbs within the past 3 months; (2) Contraindications to stroboscopic visual stimulation (e.g., epilepsy, photosensitivity); (3) Other conditions affecting balance testing (e.g., vestibular dysfunction, severe cardiovascular disease); (4) Inability to complete all assessment items. Cross-sectional study participants-CAI Group (Case Group): (1) Acute ankle injury within the past 3 months (e.g., fracture, complete ligament rupture); (2) Severe neurological disease or cognitive impairment; (3) Other musculoskeletal or neuromuscular disorders of the lower limbs (e.g., hip/knee pathologies, neuromuscular diseases); (4) Contraindications to stroboscopic visual stimulation (e.g., epilepsy, photosensitivity); (5) Use of bracing/orthotic treatment or medication interventions (e.g., corticosteroid injections) within the past 3 months; (6) Inability to complete all assessment items. Participants of the randomized controlled study: (1) Acute ankle injury within the past 3 months (e.g., fracture, complete ligament rupture, etc.); (2) Severe neurological disease or cognitive impairment; (3) Other musculoskeletal disorders of the lower limbs (e.g., hip/knee pathologies, neuromuscular diseases, arthritis, etc.); (4) Contraindications to stroboscopic visual training (e.g., epilepsy, photosensitivity, etc.); (5) Use of bracing/orthotic treatment or medication interventions (e.g., corticosteroid injections) within the past 3 months; (6) Inability to complete all training and assessment sessions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Star Excursion Balance Test ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumberland Ankle Instability Tool;Olerud-Molander Ankle Score;American Orthopedic Foot and Ankle Society Ankle-Hindfoot Score;Numeric Rating Scale;Single-leg standing stability test;Continuous single-leg jumping test;Surface electromyography test; | — |
Countries
China
Contacts
Rehabilitation Medicine Department of Huashan Hospital Affiliated to Fudan University