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The efficacy and safety of fractional QS Nd: YAG1064nm laser with different energy and number of passes in the treatment of photoaging with enlarged facial pores

The efficacy and safety of fractional QS Nd: YAG1064nm laser with different energy and number of passes in the treatment of photoaging with enlarged facial pores

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118620
Enrollment
Unknown
Registered
2026-02-09
Start date
2024-12-02
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Photoaging of the skin with enlarged facial pores

Interventions

Experimental group 3:High energy and low passes fractional QS Nd: YAG1064nm laser
Experimental group 1:Low energy and high passes fractional QS Nd: YAG1064nm laser
Experimental group 2:High energy and high passes fractional QS Nd: YAG1064nm laser

Sponsors

Zhongda Hospital Affiliated to Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.The Global Score of photoaging (GSP) was used to evaluate photodamage and the standardized rating of pores was used to evaluate pore size. Patients with baseline GSP > 2 points and facial pores rating > 3 grade were included; 2.Age >= 18 and <45 years old; 3.Be able to understand the study and voluntarily provide written informed consent; 4.Be able to complete the treatment and follow-up as required;

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women; 2.Topical or full-face treatments, laser treatments, chemical peels, dermabrasion, filler injections, or facial plastic surgery for photoaging or enlarged pores within the past 6 months; 3.Patients with contraindications to laser therapy, such as those with photosensitive diseases, cutaneous malignancies, or those with oral retinoic acid; 4.Patients with facial infectious or inflammatory disease; 5.Patients with a tendency to keloid formation; 6.Patients with a current or past history of herpes simplex; 7.Severe systemic disease and mental illness;

Design outcomes

Primary

MeasureTime frame
Overall pore-improvement score;Global Score of photoaging,GSP;

Secondary

MeasureTime frame
Recovery time of postoperative erythema and bleeding points;Other adverse reactions;High frequency skin ultrasound;Skin barrier function;Assessment of facial wrinkles;Dermoscopic photoaging score;Dermoscopic pore score;Perioperative pain score;

Countries

China

Contacts

Public ContactSu Qianya

Zhongda Hospital Affiliated to Southeast University

suqianya@163.com+86 25 83262262

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026