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Clinical study of transcranial alternating current stimulation in the treatment of cognitive impairment after stroke based on multimodal evaluation method

Clinical study of transcranial alternating current stimulation in the treatment of cognitive impairment after stroke based on multimodal evaluation method

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600118599
Enrollment
Unknown
Registered
2026-02-09
Start date
2026-02-11
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke cognitive impairment (PSCI)

Interventions

Sponsors

Xuzhou Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The age ranged from 40 to 75 years old, and all of them were examined by CT and MRI. 2. It conforms to the Expert Consensus on Post-stroke Cognitive Impairment Management issued by the China Stroke Society and the Expert Committee on Post-stroke Cognitive Impairment Management in 2021. 3. Have sufficient visual and auditory resolution to accept neuropsychological tests, near-infrared functional tests and EEG tests. 4. The subject and/or guardian informed consent and signed the consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with brain diseases other than cerebrovascular diseases, such as brain trauma, progressive supranuclear paralysis, epilepsy, chronic subdural hematoma, Huntington's disease, normal pressure hydrocephalus, brain infection, brain tumor or known brain structural abnormalities, were excluded. 2. Patients with neurodegenerative diseases, congenital and hereditary diseases were excluded. Excluding cognitive impairment caused by cerebrovascular factors such as AD, Parkinson's disease and dementia with Lewy bodies. 3. Patients with cognitive impairment caused by liver, kidney, thyroid and other systemic diseases or anemia and malnutrition were excluded. Exclude patients who can't complete the scale test, such as disturbance of consciousness, severe neurological deficit, inability to take care of themselves and severe dementia. 4. Patients who were unable to complete the scale test due to hearing, vision and language impairment and had a history of alcohol or drug abuse or dependence in the past 2 years were excluded. 5. Rule out pseudodementia caused by various other reasons. 6. Subjects who the researcher thinks cannot follow the research procedure. 7. Intracranial metal implants, magnetic disks, pacemakers or skull defects; 8. Personal or family history of epilepsy and mental illness (including febrile convulsion in infancy); 9. Pregnant.

Design outcomes

Primary

MeasureTime frame
Lowenstein Occupational Therapy Cognitive Assessment, LOTCA;

Secondary

MeasureTime frame
Montreal Cognitive Assessment Scale;EEG signal;Functional Near-Infrared Spectroscopy detection;

Countries

China

Contacts

Public ContactZunke Gong

Xuzhou Central Hospital

gongzunke@163.com+86 516 83726336

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026