Abnormal growth and development
Conditions
Interventions
Normal group:None
Case group:None
Sponsors
Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Control Group: 1. Have a household registration in Guangxi and have continuously resided there for more than 5 years; 2. Age and gender are clearly defined (based on the birth certificate); 3. In good health, without acute or chronic diseases that affect bone development (such as endocrine disorders, severe malnutrition, congenital heart disease, long-term use of hormones; acute trauma, infection, arthritis, etc.); 4. Have given informed consent and obtained the consent of the guardian. Case Group: 1. Diagnosed as having abnormal growth and development through clinical, laboratory, and imaging examinations; 2. Age between 3 and 14 years old; 3. No systematic drug treatment has been received before enrollment; 4. The children's family members have signed the informed consent form.
Exclusion criteria
Exclusion criteria: Control group: 1. Delayed or accelerated growth and development; 2. Presence of known diseases or medical history that affect bone development; 3. Born prematurely (<37 weeks) or as a low birth weight infant (<2500g), unless the researchers consider that their development has caught up with that of normal children. Case group: 1. No bone age assessment was conducted within one week before and after enrollment; 2. Received relevant drug treatment before enrollment; 3. The ultrasound images were unclear.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ossification status of the epiphysis at the bone ends;Ossification rate;Area ossification rate;Epiphyseal cartilage thickness;Duration of ultrasound examination; | — |
Countries
China
Contacts
Public ContactXinyan Li
Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region
Outcome results
None listed