Upper limb motor dysfunction after stroke
Conditions
Interventions
Experimental group:HF-rTMS combined with upper limb robot-assisted training
Control group:upper limb robot-assisted training
Sponsors
Zhejiang Rehabilitation Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients with first-episode stroke, meeting the diagnostic criteria for intracerebral hemorrhage or cerebral infarction as outlined in the Chinese Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage (2019) and the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018), and confirmed by CT or MRI examination; (2) Age between 18 and 75 years; (3) Disease duration between 2 weeks and 6 months post-stroke; (4) Modified Ashworth Scale grade of the lower limb = 1.0 as measured by the International Standard Visual Acuity Chart; (6) Mini-Mental State Examination (MMSE) score >= 21, with the ability to cooperate with treatment; (7) Stable vital signs and no progressive neurological symptoms; (8) The patient or their legal guardian has provided informed consent and signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with severe cognitive or speech impairments that prevent cooperation with training; (2) Patients with hemianopia or significant visual impairment; (3) Patients with vestibular dysfunction such as vertigo or tinnitus; (4) Patients with severe osteoarticular diseases, severe cardiopulmonary diseases, or other conditions that preclude participation in training; (5) Patients contraindicated for HF-rTMS treatment due to a history of epilepsy, metal implants, cardiac pacemakers, skull defects, or other relevant reasons; (6) Patients with other severe upper limb conditions that affect upper limb function; (7) Patients with unstable or deteriorating clinical conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fNIRS detection (Oxy-Hb);Fugl-Meyer Assessment-Upper Extremity; | — |
Secondary
| Measure | Time frame |
|---|---|
| isometric peak torque;isotonic extreme muscle endur-ance;Modified?Barthel?Index; | — |
Countries
China
Contacts
Public ContactSong Jianfei
Zhejiang Rehabilitation Medical Center
Outcome results
None listed