Atopic Dermatitis, AD
Conditions
Interventions
Test group:Apply diconide cream topically to the affected skin area(s), while applying Turtle Papa Baby Care Special Moisturizing Essence Cream to the entire bod
control group:The lesional areas were treated with diconide cream, while the blank vehicle was applied to the whole body.
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 12 Years
Inclusion criteria
Inclusion criteria: 1.Meets Williams diagnostic criteria; 2.Age 0-12 years old (inclusive), gender not limited; 3.The severity of the disease is mild to moderate (according to the actual consultation criteria of the department); 4.Subjects are not allowed to use other similar products in the skin lesion area throughout the entire study period; 5.The guardian must ensure that all basic products (including skin care lotion, cream, lotion, glucocorticoid, etc.) are not used in the skin lesion area 24 hours before the assessment; 6.The legal guardians of the subjects are able to fully understand the purpose of the trial, use medication under the guidance of a doctor throughout the entire study period, and conduct non-invasive skin physiological parameter measurements. They voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with skin diseases other than AD in the area requiring treatment; 2.Individuals with severe systemic diseases (such as cardiovascular, respiratory, digestive, nervous, endocrine, urogenital, etc.) and unstable conditions; 3.Individuals with impaired immune function (such as lymphoma, acquired immune deficiency syndrome (AIDS), etc.) or a history of malignant diseases; 4.Currently participating in other clinical studies or having participated in other clinical studies within the past 3 months, the researchers have determined that the child's compliance is poor and they are unable to complete the study as required; 5.Children who received topical medication within 7 days prior to enrollment, including calcineurin inhibitors, glucocorticoid preparations, and antihistamines; 6.Received non steroidal immunosuppressants or ultraviolet therapy within 4 weeks prior to enrollment, and systematically used glucocorticoids and antihistamines;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of Eczema Area and Severity Index;Itching Visual Simulation Score;Skin moisture content;Number of eczema relapses, recurrence rate, and time to recurrence (in days);Desquamation index (dermoscopy); | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigator Global Assessment;Transepidermal Water Loss;Quality of Life Index for Children/Infants with Skin Diseases; | — |
Countries
China
Contacts
Public ContactDeng Dan
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed