Pain during laboring
Conditions
Interventions
23? group:All patients received an initial dose of ropivacaine at 23?. The first patient received an initial bolus of ropivacaine (10 mg [0.1%]) combined with sufentanil 0.3 µg/mL in a 10 mL volume
37? group:All patients received an initial dose of ropivacaine at 37?. The first patient received an initial bolus of ropivacaine (10 mg [0.1%]) combined with sufentanil 0.3 µg/mL in a 10 mL volume
Sponsors
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged between 18 and 40 years, experiencing a single full - term pregnancy (including primiparas and multiparas), who are scheduled to receive epidural labor analgesia; 2. Cervical dilation less than 5 cm; Visual Analog Scale (VAS) score greater than 5; 3. American Society of Anesthesiologists (ASA) physical status classification grade II.
Exclusion criteria
Exclusion criteria: 1. Contraindicated for epidural labor analgesia, ropivacaine, or sufentanil; 2. Severe pregnancy - related complications (such as heart disease, gestational hypertension, diabetes, etc.); 3. Body mass index (BMI) equal to or greater than 40 kg/m^2; 4. Individuals who utilize other methods for analgesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ED90s of the initial ropivacaine bolus required for effective analgesia (VAS score <3 within 30 minutes) under dural puncture epidural ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale (VAS) score;Bromage score;Apgar score;Adverse event;Delivery related indicators; | — |
Countries
China
Contacts
Public ContactXiangsheng Xiong
Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Outcome results
None listed